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secobarbital will minimize the level or effect of diazepam intranasal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Sturdy or moderate CYP3A4 inducers may perhaps enhance fee of diazepam elimination; therefore, efficacy of diazepam might be decreased.secobarbital will lessen the level or effect of darifenacin